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Trade Name	Drug Name	Approved	Patent Expires	Indication
Opgenra	Eptotermin alfa	2009-02-19		Spondylolisthesis , Tibial fractures
Osigraft	Eptotermin alfa	2001-05-17		Spondylolisthesis , Tibial fractures

Clinical Trials

Therapeutic Areas:

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Classification:

All

Approval:

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Status:

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Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

Eptotermin alfa

healthy volunteers/patients

,

knee osteoarthritis

,

,

,

,

,

oropharyngeal neoplasms

,

alzheimer disease

,

tibial fractures

,

spondylolisthesis

,

,

femur head necrosis

,

,

intervertebral disc degeneration

,

,

sleep wake disorders

,

,

,

,

,

,

tympanic membrane perforation

,

alveolar bone loss

,

periodontal attachment loss

prostatic hyperplasia

,

,

healthy volunteers/patients

,

respiratory tract diseases

,

respiration disorders

,

,

kidney diseases

,

,

,

,

,

respiratory tract infections

,

,

premature obstetric labor

,

,

pulmonary edema

,

,

bacterial infections

,

,

hepatic insufficiency

,

,

,

multiple myeloma

,

plasma cell neoplasms

,

,

breast neoplasms

,

,

,

atherosclerosis

,

obstructive lung diseases

,

,

pancreatic neoplasms

,

,

follicular lymphoma

,

allergic rhinitis

,

pulmonary tuberculosis

,

coronary disease

,

coronary artery disease

,

myocardial ischemia

,

,

,

hepatocellular carcinoma

,

liver neoplasms

,

precursor cell lymphoblastic leukemia-lymphoma

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

sjogren's syndrome

,

,

,

,

,

,

systemic lupus erythematosus

,

,

acquired immunodeficiency syndrome

,

,

type 2 diabetes mellitus

,

human influenza

,

communicable diseases

,

,

neoplasm metastasis

,

,

parkinson disease

,

,

migraine disorders

,

,

major depressive disorder

,

depressive disorder

,

churg-strauss syndrome

,

granulomatosis with polyangiitis

,

systemic vasculitis

,

eosinophilic granuloma

,

neisseria meningitidis

,

haemophilus influenzae type b

,

restless legs syndrome

,

psychomotor agitation

,

,

,

,

,

ovarian neoplasms

,

,

,

chronic obstructive pulmonary disease

,

,

diabetes mellitus

,

,

,

,

pulmonary eosinophilia

,

prostatic neoplasms

,

growth and development

,

,

,

postherpetic neuralgia

,

renal cell carcinoma

,

human influenza

,

nutritional status

,

pneumococcal infections

,

pneumococcal pneumonia

,

,

,

systemic lupus erythematosus

,

cutaneous lupus erythematosus

,

inflammatory bowel diseases

,

,

,

tendon injuries

,

,

haemophilus influenzae

,

streptococcus pneumoniae

,

,

,

,

energy metabolism

,

endometrial neoplasms

,

,

mullerian mixed tumor

,

,

idiopathic pulmonary fibrosis

,

pulmonary fibrosis

,

,

non-small-cell lung carcinoma

,

,

neoplasm metastasis

,

,

falciparum malaria

,

ovarian neoplasms

,

brain neoplasms

,

healthy volunteers/patients

,

prostatic neoplasms

,

,

,

colorectal neoplasms

,

squamous cell carcinoma

,

multiple myeloma

,

plasma cell neoplasms

,

ovarian epithelial carcinoma

,

cutaneous malignant melanoma

,

,

type 1 diabetes mellitus

,

triple negative breast neoplasms

,

squamous cell carcinoma of head and neck

,

sickle cell anemia

,

myeloid leukemia acute

,

myeloid leukemia

,

,

,

chronic hepatitis b

,

,

primary myelofibrosis

,

hepatocellular carcinoma

,

liver neoplasms

,

fallopian tube neoplasms

,

pancreatic neoplasms

,

,

hematologic neoplasms

,

ductal carcinoma

,

circulating neoplastic cells

,

uterine neoplasms

,

uterine cervical neoplasms

,

,

streptococcus agalactiae

,

,

follicular lymphoma

,

neisseria meningitidis

,

haemophilus influenzae type b

,

invasive hydatidiform mole

,

biliary tract neoplasms

,

uveal neoplasms

,

respiratory tract diseases

,

respiration disorders

,

,

focal segmental glomerulosclerosis

,

cytomegalovirus infections

,

chronic hepatitis

,

kidney diseases

,

membranous glomerulonephritis

,

nephrotic syndrome

,

,

,

endometrioid carcinoma

,

breast diseases

,

squamous cell neoplasms

,

neurofibromatosis 2

,

acoustic neuroma

,

neurofibromatosis 1

,

neurofibromatoses

,

,

,

,

,

pulmonary tuberculosis

,

adenocarcinoma of lung

,

disease progression

,

peritoneal neoplasms

,

,

beta-thalassemia

,

,

sickle cell trait

,

essential thrombocythemia

,

polycythemia vera

,

,

,

,

,

breast neoplasms

,

,

rheumatoid arthritis

,

,

head and neck neoplasms

,

inflammatory breast neoplasms

,

,

respiratory syncytial virus infections

,

,

bacterial infections

,

,

streptococcal infections

,

,

stomach neoplasms

,

gastrointestinal neoplasms

,

digestive system neoplasms

,

infectious skin diseases

,

bacterial skin diseases

,

ductal carcinoma breast

,

renal insufficiency

,

,

,

,

urinary bladder neoplasms

,

acute coronary syndrome

,

,

rotavirus infections

,

,

mucinous adenocarcinoma

,

,

meningococcal meningitis

,

,

respiratory syncytial viruses

,

,

,

type 2 diabetes mellitus

,

diabetes mellitus

,

,

,

acquired immunodeficiency syndrome

,

,

chronic obstructive pulmonary disease

,

communicable diseases

,

,

obstructive lung diseases

,

,

dental focal infection

,

focal infection

,

,

,

immunologic deficiency syndromes

,

ventilator-associated pneumonia

,

growth and development

,

immunologic tests

,

,

alzheimer disease

,

wasting syndrome

,

,

,

insulin resistance

,

abdominal obesity

,

lipid metabolism

,

latent autoimmune diabetes in adults

,

community-acquired infections

,

,

,

staphylococcal infections

,

resistance training

,

,

,

major depressive disorder

,

depressive disorder

,

thyroid neoplasms

,

papillary thyroid cancer

,

thyroid diseases

,

clostridioides difficile

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